Constitutive opening of the Kv7.2 pore activation gate causes KCNQ2-developmental encephalopathy

Proceedings of the National Academy of Sciences, Volume 121, Issue 49, December 2024. <br/>SignificanceVariants in ion channel genes controlling neuronal excitability can cause severe neuropsychiatric disorders including developmental and/or epileptic encephalopathies (DEEs) characterized by developmental delay or regression with or without ...